By Gary M. White, MD

Eosinophilic pustular folliculitis of infancy

Eosinophilic pustular folliculitis of infancy (EPF) is a rare disorder of unknown cause. Some patients may have both EPF and infantile acropustulosis. Given the similar histologic appearance, they may represent the same disease in different sites [BJD 1996;135;807].


Sterile vesicopustules and crusting on the scalp of an infant is characteristic. Papulopustular or erythematous lesions often occur elsewhere. Onset is usually several days to weeks after birth.


A medium to high-potency topical steroid is usually effective. Dapsone has been used but is rarely needed.

Additional Pictures

Eosinophilic pustular folliculitis of infancy


Eosinophilic pustular folliculitis in infancy: Report of a new case. Dermatology Online Journal 18(10)


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