DISSEMINATED INTRAVASCULAR COAGULATION
Disseminated Intravascular Coagulation (DIC) is not a disease itself but an acquired syndrome, caused by a variety of underlying disorders. Typical findings include:
- Abnormal bleeding
- Shock or microcirculatory disorder
- Unexplained organ failure
- Decreased (especially recently) platelet count
- Elevated D-dimer
- Prolongation of PT and APTT
- Low fibrinogen
Widespread clotting and bleeding results in bruising, purpura, and necrotic lesions of the skin. Mortality is high.
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