DIFFUSE DERMAL ANGIOMATOSIS
By Gary M. White, MD
Diffuse dermal angioatosis (DDA) is a benign reactive proliferation of vessels that commonly presents int he skin with painful livedoid plaques with ulceration. On biopsy, a diffuse endothelial cell hyperplasia is seen. It seems to be part of reactive angiomatosis.
In one report [JAAD 2001;45;462] a woman with multiple ulcers on the breasts was thought to have diffuse dermal angiomatosis as diagnosed by biopsy.
The patient responded to isotretinoin 80 mg/day with clearing after 2 months.
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