By Gary M. White, MD

Dermatopathia pigmentosa reticularis (DPR) is a very rare autosomal dominant ectodermal dysplasia characterized by generalized reticulate hyperpigmentation, nonscarring alopecia, and onychodystrophy.


Fourteen and 11-year-old siblings presented with generalized reticulate pigmentation since birth as well as generalized sweating and recurrent blisters, mainly over the soles. Furthermore, they reported progressive hair thinning and abnormal nail growth. Indian J Dermatol 2016;61:468


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