By Gary M. White, MD

CREST Syndrome

The CREST syndrome is a subgroup of systemic scleroderma. Sclerodactyly or induration and sclerosis of the skin of the fingers occurs. The skin is smooth and shiny, and the fingers tapered. Anticentromere antibodies are most characteristic of CREST but may also be found in systemic scleroderma patients.



The telangiectatic matting may be treated with laser. The calcinosis cutis may be treated effectively with diltiazem 240-480 mg/day [Arth Rheum 1995;38;1646] or by carbon dioxide laser [BJD 1996;135;302].

Treatment of Digital Ulcers

See scleroderma.

Additional Photos

CREST Syndrome

CREST Syndrome CREST Syndrome

CREST Syndrome

Raynaud's phenomenon in a patient with CREST syndrome.
CREST Syndrome


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