COCCIDIOIDOMYCOSIS

By Gary M. White, MD

Coccidioidomycosis A cutaneous ulcer on the shoulder caused by coccidioidomycosis.


Coccidioidomycosis is caused by infection with Coccidioides immitis. In the US, coccidioidomycosis infection usually occurs in the Southwest, in states such as Arizona, New Mexico, and in the San Joaquin Valley of California. Infection initially occurs through the respiratory tract. Infection may be limited to the lungs, or may disseminate in about 1 out of 200 persons. Those immunocompromised (e.g., HIV, organ transplant, hematogenous malignancy), pregnant women, or those of African American, Filipino, or Mexican descent are at higher risk.

Clinical

Skin lesions usually appear as verrucous nodules. Pulmonary coccidioidomycosis can cause edematous papules, nodules, and plaques to develop abruptly during the onset of the acute febrile illness. Ulcers may develop. Pulmonary coccidioidomycosis can also precipitate erythema nodosum.

Treatment

Consultation with an infectious disease specialist is recommended. In the past, treatment involves amphotericin B until a clinical response is achieved and antibody titers decline. Then, the amphotericin B can be replaced with an oral azole such as itraconozole or fluconazole.

Additional Pictures

Erythema nodosum from Coccidioidomycosis infection.
Coccidioidomycosis

RegionalDerm

Homepage | FAQs | Use of Images | Contact Dr. White


It is not the intention of RegionalDerm.com to provide specific medical advice, diagnosis or treatment. RegionalDerm.com only intends to provide users with information regarding various medical conditions for educational purposes and will not provide specific medical advice. Information on RegionalDerm.com is not intended as a substitute for seeking medical treatment and you should always seek the advice of a qualified healthcare provider for diagnosis and for answers to your individual questions. Information contained on RegionalDerm.com should never cause you to disregard professional medical advice or delay seeking treatment. If you live in the United States and believe you are having a medical emergency call 911 immediately.