COBB SYNDROME

By Gary M. White, MD


Cobb syndrome is the presence of a spinal arteriovenous malformation and a vascular skin lesion, e.g. port wine stain, affecting the corresponding dermatome.

Clinical

Cutaneous lesions that have been reported include angiomas, angiokeratomas, angiolipomas, and lymphangioma circumscriptum.

The intraspinal lesions are usually AVMs and rarely angiomas. Neurologic symptoms develop most commonly in late childhood, but may occur at any age. They may present with sudden onset of weakness with rapid progression, monoparesis or sudden-onset paraplegia or quadriplegia. Bladder and bowel involvement is common but tends to occur late.

References

Patient with both the Sturge-Weber and the Cobb syndrome. The port-wine stain over the spinal canal corresponds to the Cobb syndrome.Trans Am Ophthalmol Soc. 2013 Sep; 111: 180–215

RegionalDerm

Homepage | FAQs | Use of Images | Contact Dr. White


It is not the intention of RegionalDerm.com to provide specific medical advice, diagnosis or treatment. RegionalDerm.com only intends to provide users with information regarding various medical conditions for educational purposes and will not provide specific medical advice. Information on RegionalDerm.com is not intended as a substitute for seeking medical treatment and you should always seek the advice of a qualified healthcare provider for diagnosis and for answers to your individual questions. Information contained on RegionalDerm.com should never cause you to disregard professional medical advice or delay seeking treatment. If you live in the United States and believe you are having a medical emergency call 911 immediately.