By Gary M. White, MD
Clear cell papulosis (CCP) causes small white papules most typically on the abdomen of a child.
The child has multiple white papules, round or oval, with a smooth, flat surface, 2-10 mm in diameter. The number may range from 5 to more than 100. The lower abdomen is a favored site, but the chest, shoulder and inguinal area are also affected.
Histology shows a proliferation of clear cells in the basal epidermis, larger than adjacent keratinocytes.
It is assumed that this disease spontaneously disappears before adulthood. In one long term study with a median follow-up duration of 11.5 years, regression of skin lesions was observed in 85.7% of patients [JAAD August 2010 Volume 63, Issue 2, Pages 266–273].
A 2 year old boy with over 100 white papules over the lower abdomen. JAAD August 2010 Volume 63, Issue 2, Pages 266–273
A healthy 2-year-old boy with asymptomatic, hypopigmented eruption on the abdomen and in the pubic area. His parents initially noticed a few white spots superior to the scrotum at age three months and the lesions progressively increased in number and spread onto the abdomen. Dermatology Online Journal
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