By Gary M. White, MD

Chrysiasis A mauve discoloration about the periorbital area is typical.

Chrysiasis is a rare discoloration of the skin in patients who have received long term gold therapy.


The bluish color is most prominent about the eyes and in sun-exposed areas. Laser-induced localized chrysiasis may occur immediately after treatment with the Q-switched ruby laser, the Alexandrite laser and the Nd:YAG laser in patient previously treated with gold. Such patients will develop blue macules at the laser treatment site immediately after therapy.


Sun protection is in order. Treatment may be unsatisfactory. Use of the pulsed dye laser and long-pulsed Alexandrite laser may be tried, but obviously, worsening of the condition with laser therapy must be considered.


Q-Switched Alexandrite Laser-induced Chrysiasis. J Clin Aesthet Dermatol. 2015 Sep; 8(9): 48–53


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