DISSEMINATED CANDIDIASIS

By Gary M. White, MD


Sepsis caused by Candida is a serious infection that is often fatal. The patient is usually very sick. Most are immunocompromised.

Clinical

A very ill, immunocompromised patient with a smattering of erythematous to purpuric papulonodules is typical. Pustules may be seen. In advanced cases, hemorrhagic bulla that progress to necrotic lesions may occur (ala ecthyma gangrenosum).

Diagnosis

A touch prep of a skin biopsy stained with KOH or Giemsa may show the organisms. Blood culture is positive less that half of the time.

Treatment

Intravenous anti-yeast therapy should be given in consultation with an infectious disease specialist.

References

Ecthyma gangrenosum-like lesions Dermatology Online Journal, 22(1)

Diffuse erythematous papules and purpuric/necrotic lesions on feet. Dermatol Argent 2010;16(5):337-343

Disseminated Candida krusei infection in a patient with acute myeloid leukemia Dermatology Online Journal 21;11


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