BROOKE-SPIEGLER SYNDROME

By Gary M. White, MD

Brooke-Spiegler Syndrome: Cylindromas of the scalp and trichoepitheliomas of the face Courtesy Michael O. Murphy, MD


Brooke-Spieler Syndrome (BSS) is the association of cylindromas with multiple facial trichoepitheliomas and occasionally other adnexal tumors e.g. spiradenomas or EICs [AD 2017;153;826].

Clinical and Treatment

Please see individual entries for cylindromas and trichoepitheliomas. Genetic counseling should be done.

Genital tumors are occasionally found in female patients with CYLD mutations and include EICs, cylindromas and eccrine spiradenomas [JAMA Derm 2017;153;826].

RegionalDerm

Homepage | FAQs | Use of Images | Contact Dr. White


It is not the intention of RegionalDerm.com to provide specific medical advice, diagnosis or treatment. RegionalDerm.com only intends to provide users with information regarding various medical conditions for educational purposes and will not provide specific medical advice. Information on RegionalDerm.com is not intended as a substitute for seeking medical treatment and you should always seek the advice of a qualified healthcare provider for diagnosis and for answers to your individual questions. Information contained on RegionalDerm.com should never cause you to disregard professional medical advice or delay seeking treatment. If you live in the United States and believe you are having a medical emergency call 911 immediately.