By Gary M. White, MD

basosquamaous cell carcinoma A large, 11 x 4 cm basosquamaous cell carcinoma on the chest.

The basosquamous carcinoma (BSC) is an aggressive epithelial neoplasm with features of both basal cell carcinoma and squamous cell carcinoma, with a tendency toward local recurrence and a propensity for lymph node and distant metastases.


The clinical appearance is usually that of a BCC. Specifically, papules, nodules and plaques with crusting, bleeding and ulceration are typical. A rolled border may be seen.

Differential Diagnosis

Histologically, basaloid SCC and basoquamous cell carcinoma must be distinguished.


Mohs surgery is the treatment of choice. Published recurrence rates are 12% to 51% for surgical excision and 4% for Mohs micrographic surgery.


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