DIFFUSE INDURATION FROM BALICATIB
By Gary M. White, MD
Balicatib has been studied in women to prevent loss of vertebral and femoral bone mineral density and to increase bone strength. During the trials, morphea-like changes of the skin occurred. As documented in one report [JAAD 2012;66;e89], nine patients of 709 treated with balicatib developed skin hardening. No such events were observed in patients taking placebo or the lowest balicatib dose. After discontinuation of balicatib, skin changes resolved completely in 8 and partially in one patient.
J Am Acad Dermatology Volume 66, Issue 3, Pages e89–e96, March 2012
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