By Gary M. White, MD
Second Generation (and less sedating)
- Cetirizine (Zyrtec in the US--OTC) 10 mg po daily
- Levocetirizine (Xyzal) 5 mg in the evening. By prescription US
- Fexofenadine (Allegra in the US--OTC) 60 mg BID
- Loratadine (Claritin in the US--OTC) 10 mg tablets, one po Q day
- Desoloratadine (Clarinex) 5 mg
First Generation (sedating)
- Diphenhydramine (Benadryl 25 mg Q 1-3 hours up to 12/day
- Chlorpheniramine (4 mg)
- Hydroxyzine 10–25 mg
- Doxepin 25-50 mg QHS by prescription in the US
The dosing for children's Benadryl (12.5 mg/ 5 cc) is 1 mg/kg/dose. For example, a 12.5 kg or 27 lb. infant would get 5 cc per dose. Don't give to infants or young children for colds as no proven benefit. For allergies or hives, the lower age limit is controversial. Some say no younger than 2 years of age, others say 1 year of age [e.g. Children's Hospital St. Louis], and still some say it is fine to give to infants regardless of age.
There also is a chewable 12.5 mg tablet.
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