By Gary M. White, MD

Second Generation (and less sedating)

First Generation (sedating)

Children's Benadryl

The dosing for children's Benadryl (12.5 mg/ 5 cc) is 1 mg/kg/dose. For example, a 12.5 kg or 27 lb. infant would get 5 cc per dose. Don't give to infants or young children for colds as no proven benefit. For allergies or hives, the lower age limit is controversial. Some say no younger than 2 years of age, others say 1 year of age [e.g. Children's Hospital St. Louis], and still some say it is fine to give to infants regardless of age.

There also is a chewable 12.5 mg tablet.


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