By Gary M. White, MD

Amiodarone Pigmentation of the Skin

Chronic administration of amiodarone can cause a bluish-gray pigmentation usually in the sun-exposed areas.


Various Q-switched lasers may prove effective (e.g., ruby, YAG, alexandrite). In one report, a man with amiodarone pigmentation of the face responded to treatment with the Q-switched neodymium:yttrium-aluminum-garnet (Nd:YAG) laser [J Drugs Dermatol. 2011 Nov;10(11):1316-9].


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