By Gary M. White, MD

Albright's hereditary osteodystrophy (AHO) is a syndrome which combines pseudohypoparathyroidism (secondary to end-organ resistance to PTH), decreased calcium, increased PO4, short stature, obesity, round face, and brachydactyly. The main skin finding is bone formation (osteoma cutis--OC). In contrast to actual hypoparathyroidism, the PTH level is normal or even increased.


The lesions of osteoma cutis may occur anywhere, but have a predilection for sites around large joints and areas of trauma. The lesions initially may be pinpoint in size and then enlarge, e.g., becoming 5-8 cm in size. Shortening of the metacarpal bones may occur in patients with AHO.


With regard to treatment of the osteoma cutis, see osteoma cutis.


BMJ. 2008 Jun 7; 336(7656): 1298–1302.

A 68-year-old woman with a history of mild acne vulgaris as a teenager presented complaining of multiple facial lesions. These asymptomatic lesions first appeared at the age of 16 years. Her past medical history was notable for hysterectomy because of uterine calcification in her 50s. Her face was typical shape but hadmany scattered one to three millimeter skin-colored papules apparent on the face, cheeks, and forehead. Notably, the fifth digits of both the right and left hands were significantly shortened Dermatology Online Journal 23(3)


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